Which statement about insulin administration and insulin types helps prevent lipodystrophy?

Which statement about insulin administration and insulin types helps prevent lipodystrophy?

• A. Rotate injection sites regularly
• B. Use the same site for all injections to ensure consistency
• C. Injecting at a single site reduces pain
• D. Increasing injection angle reduces absorption variability

Answer: (A)

Rotating injection sites regularly helps prevent lipodystrophy. Repeated insulin injections in the same small area can cause changes in the subcutaneous fat, especially lipohypertrophy, where fatty tissue thickens into a lump. These tissue changes disrupt consistent insulin absorption, making its effect unpredictable and increasing the risk of blood glucose swings. By rotating among different sites or moving around a single area, you limit local trauma, give tissue time to recover, and maintain more uniform insulin absorption. This is why spreading injections across multiple sites (abdomen, thigh, arm, etc.) and varying the exact spot within a region is recommended. Using the same site for all injections would promote lipodystrophy, so that’s not a good approach. Injecting at a single site doesn’t reliably reduce pain and doesn’t address the absorption variability caused by tissue changes. Injection angle matters for depth and absorption in different body types, but it isn’t the main strategy to prevent lipodystrophy.

Rotating injection sites regularly helps prevent lipodystrophy. Repeated insulin injections in the same small area can cause changes in the subcutaneous fat, especially lipohypertrophy, where fatty tissue thickens into a lump. These tissue changes disrupt consistent insulin absorption, making its effect unpredictable and increasing the risk of blood glucose swings. By rotating among different sites or moving around a single area, you limit local trauma, give tissue time to recover, and maintain more uniform insulin absorption. This is why spreading injections across multiple sites (abdomen, thigh, arm, etc.) and varying the exact spot within a region is recommended.

Using the same site for all injections would promote lipodystrophy, so that’s not a good approach. Injecting at a single site doesn’t reliably reduce pain and doesn’t address the absorption variability caused by tissue changes. Injection angle matters for depth and absorption in different body types, but it isn’t the main strategy to prevent lipodystrophy.